Crohn's disease is a granulomatous disease of the gastrointestinal tract, especially terminal ileum, but may involeve the lip, mouth, anus, skin, liver and bone. The skin is a common site of extraintestinal involvement in Crohn's disease, with
the
perianal. perineal, and peristomal areas most frequently affected. Vulvar involvement, however, is an uncommon extraintestinal manifestantion of Crohn's disease.
We report a case of a 16-year-old girl with Crohn's disease of the vulva and perianal region. A histopathologic study of the descending colon and vulvar skin showed noncaseating granulomatous reactions composed of lymphocytes. epithelioid cells
and
giant cells. We were able to make the diagnosis of Crohn's disease of the vulva and the patient was treated with prednisolone and metronidazole. (Kor J Dermatol 1992;30 (2) : 267-271)
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